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Literature Review: PGT-A Testing


Abstract 


Preimplantation Genetic Testing for Aneuploidy (PGT-A) is an elective add-on in the IVF process that screens embryos for aneuploidy before they are transferred. It is performed with the hope that reducing the use of aneuploid embryos will also reduce miscarriage risk. However, there is insufficient evidence to recommend its routine use to all infertile patients, as studies on its outcomes provide inconsistent results. This review of the literature will discuss the existing research and how addressing gaps in that research could provide meaningful information to guide provider and patient decisions. 


Key words 

In Vitro Fertilization, PGT-A, Mosaicism, Aneuploidy, Advanced Maternal Age, Recurrent Pregnancy Loss


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